Understanding the inflammatory response of the airways to inhaled substances is paramount to assessing the long-term adverse effects on lung health. Many inhaled substances reach the small or distal airways, and it is in this region of the lung where alveolar macrophages are the first responders to these substances and play a pivotal role in homeostasis and regulating inflammation. Therefore, to ensure a comprehensive safety of inhaled products, it’s imperative to employ immune-competent models that capture the nuanced responses of alveolar macrophages.

At ImmuONE, we specialise in alveolar macrophage models and responses. Our services, products and experts enable you to understand, in detail how alveolar macrophages respond to inhaled chemicals/particulates and support classification of the response as being adaptive or adverse.